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Randomized conditional p-values are uniform

Statement

Under the simple null and the supplied conditional law in Randomized conditional upper-tail p-values, for every u∈[0,1], P0(pU≤u∣σ(S))=uP0-almost surely, while the nonrandomized upper-tail value satisfies P0(p0≤u∣σ(S))≤uP0-almost surely. Thus the randomized value is conditionally uniform and the inclusive-tail value is conditionally superuniform, including when the conditional law has atoms.

Facts & Assumptions

Given: A simple null law P0, statistics S,T, a supplied conditional law kernel K(s,⋅) of T given S, and an independent uniform randomizer U.

[F1]

The randomized and nonrandomized values are pU=K(S,(T,∞))+UK(S,{T}) and p0=K(S,[T,∞)). Randomized conditional upper-tail p-values

[F2]

The kernel K(s,⋅) is a conditional law of T given S. Conditional law given a random element

[F3]

U is independent of the pair (S,T). Independent random elements

[F4]

For sigma-finite measures, the product measure exists and has the rectangle formula. For sigma-finite factors, the product measure exists, has the rectangle formula, is sigma-finite, and is unique

[F5]

Measurable rectangles generate the product sigma-algebra. The product sigma-algebra and its finite iterates

[F6]

Equality of finite measures on a generating pi-system extends to the generated sigma-algebra. Dynkin's pi-lambda theorem

[F7]

For any real law with CDF F and independent uniform W, F(Y−)+W(F(Y)−F(Y−)) is uniform. Randomizing across CDF jumps gives a uniform variable

[A1]

The randomizer has the uniform law on [0,1], namely P(U≤u)=u for u∈[0,1]; this is stipulated in the p-value definition.

Proof

1.1F2F3F4F5F6A1

For each s, let Λs:=K(s,⋅)⊗λ, where λ is the uniform law of U. By [F4] this is a probability measure with rectangle values Λs(C×D)=K(s,C)λ(D). For A∈σ(S) and Borel C,D, the conditional-law identity [F2] gives ∫AΛS(C×D) dP0=λ(D)P0(A∩{T∈C}). Independence in [F3] makes the right side P0(A∩{T∈C,U∈D}). The class of product-Borel sets where the evaluation s↦Λs(E) is measurable and every such conditional identity holds is a Dynkin system: complements subtract from the probability-one whole-space evaluation, and disjoint unions follow by countable additivity and increasing limits. It contains the generating rectangles, so [F5] and [F6] extend measurability and the conditional identity to every product-Borel set. Thus ΛS is a conditional law of (T,U) given S.

2.1A1F1F7step 1.1algebra

For almost every conditioning value s, the conditional law just constructed makes T have law K(s,⋅) and keeps U independent uniform. Write Fs(t):=K(s,(−∞,t]) and Δs(t):=Fs(t)−Fs(t−). By [F7], V=Fs(T−)+(1−U)Δs(T) is uniform, since 1−U is also uniform. The p-value formula in [F1] gives pU=1−V, so pU is conditionally uniform.

3.1F1step 2.1A1algebra∎

For the same s, p0=1−Fs(T−) and pU=1−Fs(T−)−(1−U)Δs(T)≤p0. Hence {p0≤u}⊆{pU≤u} conditionally on S=s. Step 2.1 gives P0(p0≤u∣S=s)≤u. This holds for each u∈[0,1] and almost every conditioning value, proving conditional superuniformity.

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