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Minimum-intensity coupling of two birth-death chains
Statement
Assume Countable Choice and Dependent Choice. On , let both chains have birth increment and death increment . Set Starting from and using unlimited candidate budget, the minimum-intensity coupling has at the first paired event three possibilities, each at rate : shared birth to , shared death to , or -only death to . Thus its uncensored first paired-event time is and each possibility has probability ; a finite-horizon call records it only when it occurs before the horizon. The coordinate path marginals remain the exact and reaction laws.
Facts & Assumptions
Given: Countable Choice (The Axiom of Countable Choice ()), Dependent Choice (The axiom of dependent choice: a relation in which every element is related to something admits an -indexed chain), the two finite-state birth-death systems, initial pair , and the minimum-intensity coupling with unlimited candidate budget.
The propensity definition requires active poststates to lie in the finite state set, and rates determine the reaction generator. (Finite-channel reaction propensity systems and their generator)
The coupling constructs shared events at the minimum channel rate and residual events at the positive rate differences. (Minimum-intensity coupling of reaction networks)
Under Countable Choice and Dependent Choice and with unlimited candidate budget, both coupled coordinate processes have the exact path laws of their respective Gillespie chains. (The minimum-intensity reaction coupling preserves both marginals)
Under Countable Choice and Dependent Choice, for a fixed state, pairwise-disjoint accepted mark sets with product-measurable time-mark regions and total measure under a rate- candidate stream give first-event survival and channel-specific event probabilities proportional to the set measures. The algorithm's event portions here are fixed intervals, so these regions are product-measurable. (Dominating thinning has the prescribed reaction law)
Proof
For both systems, a positive birth rate occurs only at and moves to ; a positive death rate occurs only at and moves to . All rates are nonnegative and finite, so [F1] gives valid finite-state systems.
At the birth rates are , hence [F2] gives shared birth rate . The death rates are , hence shared death rate and -only death rate ; the -only death rate is . There are no other event types, so the total paired-event rate is .
The algorithm's birth envelope is , and its death envelope is , so the total candidate rate is . At the fixed pair the three disjoint event-mark portions have total length ; [F4] gives first-event survival and assigns each equal-length portion probability conditional on an event. Their state updates are respectively , , and .
The marginal theorem [F3] applies because the budget is unlimited and the finite rates supply the bounds and . It identifies each coordinate path with its own Gillespie reaction law, completing the example.
Depends on
- Minimum-intensity coupling of reaction networks
- The Axiom of Countable Choice ($\mathrm{AC}_\omega$)
- The axiom of dependent choice: a relation in which every element is related to something admits an $\mathbb{N}$-indexed chain
- Finite-channel reaction propensity systems and their generator
- The minimum-intensity reaction coupling preserves both marginals
- Dominating thinning has the prescribed reaction law
Used by
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Sources
- David F. Anderson, Introduction to Stochastic Processes with Applications to Biology (standard reference, not scraped)