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Uniform Cox partial-likelihood Hessian convergence
Statement
Use the IID bounded-covariate setup and the risk-support and compact-set hypotheses of Integrated and conditional uniform convergence of Cox risk-set sums. For each subject let and . Assume the continuous counting-process contract of Simple counting-process intensity and compensator contract for each on one common filtration, and assume no two subjects fail at the same time. Write , , and . For , let using zero values when a finite-sample denominator is zero. Let and . Define Then the partial log-likelihood Hessian satisfies The map is continuous. In particular, , where
Facts & Assumptions
Given: The integrated risk-set hypotheses, fixed , bounded predictable covariates, integrable , no tied failures, and the per-subject continuous counting-process contracts in the Statement.
Cox proportional-hazards model and partial likelihood: the no-tie partial likelihood uses and weights .
Integrated and conditional uniform convergence of Cox risk-set sums: the risk sums, weighted means and covariances converge in expected squared error integrated against , uniformly in parameter, and empirical denominators have a uniform positive bound with probability tending to one.
Simple counting-process intensity and compensator contract: for a simple counting process, the specified continuous compensator is , and the model contract assumes is a square-integrable martingale.
Brackets of a compensated simple counting process: for that contract, is a martingale and the continuous predictable bracket is .
L² extension of the predictable counting-process integral: a predictable integrand with finite has a square-integrable integral with .
Stochastic order and convergence notation for finite-dimensional random vectors: means the sequence is bounded in probability.
Progressively measurable and predictable processes: bounded predictable processes are jointly measurable, and deterministic Borel functions of time are predictable.
Pathwise identity for bounded predictable counting-process integrals: bounded predictable stochastic integrals equal their pathwise expressions, and for nonnegative predictable .
Cauchy-Schwarz inequality for : on every measure space, for square-integrable .
AC is inherited through the counting-process martingale and conditional-expectation interfaces. The Axiom of Choice
Proof
At each recorded failure the risk set contains its failing subject, so its denominator is positive for every , even if risk sets are empty at other times. Differentiate the finite sum defining to obtain and . Define on empty risk sets. It is predictable, its entries are bounded by , and [F5] permits the pathwise decomposition against .
Since subjects have no simultaneous failures, is simple; is square-integrable and has continuous compensator . Its total compensator satisfies , and by [F5]. Thus the aggregate contract holds and [L2]–[L3] apply. For each fixed , including the random predictable , their isometry bounds .
The parameter maps have a deterministic Lipschitz bound independent of : on a nonempty risk set, differentiating a weighted expectation of a bounded coordinate gives , bounded by ; apply this to and the covariance product. An empty risk set is empty for every parameter, so its zero convention also has this bound. The population maps satisfy the same bounds by differentiation under their bounded expectations and positive denominators. A finite -net of and step 2.1 control on net points. Between points, [F5] bounds the difference by ; letting proves its uniform parameter convergence to zero. The population Lipschitz bound and integrability of also prove continuity of .
The compensator term equals . Its difference from is bounded uniformly in parameter by [F6] and [F2]'s expected integrated squared-error convergence make this bound tend to zero in L¹ and hence probability (if , the bound is zero directly). Combine this with step 3.1 and the Hessian identity in step 1.1 to prove the stated uniform parameter limit. Finally by direct multiplication of by .
Depends on
- Cauchy-Schwarz inequality for $L^2$
- The Axiom of Choice
- Cox proportional-hazards model and partial likelihood
- Simple counting-process intensity and compensator contract
- Stochastic order and convergence notation for finite-dimensional random vectors
- Progressively measurable and predictable processes
- Pathwise identity for bounded predictable counting-process integrals
- Integrated and conditional uniform convergence of Cox risk-set sums
- Brackets of a compensated simple counting process
- L² extension of the predictable counting-process integral
Used by
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Sources
- Lu Tian, STAT331 Example of Martingale CLT with Cox's Model, PDF pp. 1–7 (standard reference, not scraped)
- Lu Tian, STAT331 Revisiting Cox's PH Model: Asymptotic Theory, PDF pp. 1–5 and 9–10 (standard reference, not scraped)
- Qiqing Yu, Survival Analysis (Lecture Notes), §5.2, PDF pp. 58–63 (standard reference, not scraped)