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Cox score martingale representation and random-risk-mean replacement
Statement
Use the IID bounded-covariate model, risk-support hypotheses of Integrated and conditional uniform convergence of Cox risk-set sums, the no-tie event process, and the per-subject counting-process contracts of Simple counting-process intensity and compensator contract. Let where each vector integral is defined coordinatewise in L². If is the partial-likelihood score, then The are IID, centered, square-integrable vectors with covariance matrix . In particular, . The replacement of the random risk-set mean by is part of the conclusion.
Facts & Assumptions
Given: The model and integrated risk-set conditions stated above, plus the finite-horizon square-integrable counting-process contracts with continuous compensators, no tied failures, and .
Cox proportional-hazards model and partial likelihood: the no-tie partial likelihood is the product of event weights divided by their risk-set weight sums, with .
Integrated and conditional uniform convergence of Cox risk-set sums: defines the empirical and population weighted risk means, sets each to zero at a zero denominator, and proves expected squared-error convergence integrated against , with positive empirical denominators uniformly with probability tending to one.
Simple counting-process intensity and compensator contract: is a square-integrable martingale with continuous compensator under the stated model contract.
Elementary predictable integral against a counting-process martingale: for predictable step integrands the stochastic integral is the finite sum of coefficients times martingale increments.
Brackets of a compensated simple counting process: is a martingale and .
L² extension of the predictable counting-process integral: a predictable integrand with finite compensator energy has a square-integrable martingale integral with the bracket isometry.
Stochastic order and convergence notation for finite-dimensional random vectors: a sequence is when it is bounded in probability.
Progressively measurable and predictable processes: predictable processes are jointly measurable and deterministic Borel functions of time are predictable.
Pathwise identity for bounded predictable counting-process integrals: bounded predictable completed stochastic integrals equal their pathwise expressions.
AC is inherited from the counting-process and conditional-expectation interfaces. The Axiom of Choice
Proof
Differentiating the finite product in Cox proportional-hazards model and partial likelihood gives By [F4], this pathwise integral can be decomposed as the L² stochastic integral and its compensator integral. Writing , the compensator contribution is zero because whenever the risk denominator is positive; outside the risk set every summand is zero.
Set and . The process is predictable by [F1]–[F3] and the deterministic measurability of . For bounded predictable step approximations, the finite-sum definition [L2] is linear in the integrator; the isometry [L4] and pass that identity to the L² limits. Thus . No simultaneous failures make a simple counting process, and the sum of the subject contracts is a square-integrable martingale contract with compensator .
The predictable aggregate integrand is bounded by . Its compensator energy satisfies by [F2]'s integrated squared-error conclusion, without a time supremum. Thus [L4] shows the aggregate correction in step 2.1 tends to zero in L² after division by , and therefore is .
By [F4], equals the event sum minus the compensator Lebesgue integral with integrand . Both are measurable functions of the th subject record and the deterministic function , so the are IID. The integral isometry gives mean zero. Applying its scalar form to each coordinate and polarizing the identity gives the cross-coordinate isometry, hence . The equality follows by expanding the outer product and using . Independence and centering give . For , nonnegativity gives , so the normalized sum is by [L5]. Combining this with step 3.1 proves the representation and the stated moment properties.
Depends on
- The Axiom of Choice
- Cox proportional-hazards model and partial likelihood
- Simple counting-process intensity and compensator contract
- Elementary predictable integral against a counting-process martingale
- Stochastic order and convergence notation for finite-dimensional random vectors
- Progressively measurable and predictable processes
- Pathwise identity for bounded predictable counting-process integrals
- Integrated and conditional uniform convergence of Cox risk-set sums
- Brackets of a compensated simple counting process
- L² extension of the predictable counting-process integral
Used by
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Sources
- Lu Tian, STAT331 Example of Martingale CLT with Cox's Model, PDF pp. 1–7 (standard reference, not scraped)
- Lu Tian, STAT331 Revisiting Cox's PH Model: Asymptotic Theory, PDF pp. 1–5 and 9–10 (standard reference, not scraped)
- Qiqing Yu, Survival Analysis (Lecture Notes), §5.2, PDF pp. 58–63 (standard reference, not scraped)